Evolutionary Potential of a Duplicated Repressor-Operator Pair: Simulating Pathways Using Mutation Data
نویسندگان
چکیده
منابع مشابه
Evolutionary Potential of a Duplicated Repressor-Operator Pair: Simulating Pathways Using Mutation Data
Ample evidence has accumulated for the evolutionary importance of duplication events. However, little is known about the ensuing step-by-step divergence process and the selective conditions that allow it to progress. Here we present a computational study on the divergence of two repressors after duplication. A central feature of our approach is that intermediate phenotypes can be quantified thr...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2006
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.0020058